CasNo： 37148-48-4
MF： C8H7Cl2NO
Appearance： white to light yellow crystal powder
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Storage |
4-Amino-3,5-dichloroacetophenone should be stored in a cool, dry place in a small, well filled, well-closed container, protected from light. When a partially filled container is used, the air should be replaced by nitrogen or another inert gas. 4-Amino-3,5-dichloroacetophenone oxidizes on exposure to air, resulting in an increase in the peroxide value. |
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Preparation |
4-Amino-3,5-dichloroacetophenone was synthesized by chlorination of 4-aminoacetophenone. Add 4-aminoacetophenone and acetic acid (80%) into the reaction pot, stir and dissolve, quickly add chlorine-containing glacial acetic acid solution, the temperature of the addition is 5°C. After the addition is completed, immediately put into ice water to precipitate, filter, and wash with water to obtain the crude product. Recrystallize with ethanol to obtain the finished product of 4-Amino-3,5-dichloroacetophenone. |
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Application |
4-Amino-3,5-dichloroacetophenone is a compound useful in organic synthesis. |
InChI:InChI=1/C8H7Cl2NO/c1-4(12)5-2-6(9)8(11)7(10)3-5/h2-3H,11H2,1H3
The invention discloses a phenylethanola...
The invention specifically relates to a ...
The invention relates to a stable isotop...
acetyl chloride
2,6-Dichloroaniline
1-(4-amino-3,5-dichlorophenyl)-1-ethanone
| Conditions | Yield |
|---|---|
|
With iron(III) chloride; In chloroform; at 0 - 20 ℃; for 6h;
|
88.6% |
p-aminobenzophenone
1-(4-amino-3-chlorophenyl)ethan-1-one
1-(4-amino-3,5-dichlorophenyl)-1-ethanone
| Conditions | Yield |
|---|---|
|
With N-chloro-succinimide; In acetonitrile; at 20 ℃; for 3.5h;
|
80% 18% |
|
With N-chloro-succinimide; In acetonitrile; at 20 ℃; for 4.5h;
|
20% 45% |
p-aminobenzophenone
chlorine
acetic acid
acetyl chloride
3,5-dichloro-4-phenylcarbamoylaminoacetophenone
(E)-4-amino-3,5-dichloro-γ-oxo-benzenebutenoic acid
2-(3,5-dichlorophenyl)acetaldehyde
3,5-dichloro-4-(N,N-diethylamino)acetophenone
