• Product Name4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt
  • CasNo. 6640-22-8
  • MFC23H14Na2O6
  • MW432.34
  • Purity
  • Appearancepale yellow to yellow powder
  • Packing
  • Contact usInquiry

Product Details

CasNo: 6640-22-8

MF: C23H14Na2O6

Appearance: pale yellow to yellow powder

Quality Factory Supply Top Purity 6640-22-8 with Efficient Delivery

  • Molecular Formula:C23H14O6*2Na
  • Molecular Weight:432.34
  • Appearance/Colour:pale yellow to yellow powder 
  • Vapor Pressure:2.13E-17mmHg at 25°C 
  • Melting Point:300 °C 
  • Boiling Point:642.7 °C at 760 mmHg 
  • Flash Point:356.5 °C 
  • PSA:120.72000 
  • Density:1.55[at 20℃] 
  • LogP:1.72200 

4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt(Cas 6640-22-8) Usage

Flammability and Explosibility

Notclassified

Biological Activity

Pamoic acid disodium salt is a GPR35 agonist. Induces GPR35 internalization and activates ERK1/2 (EC50 values are 22 and 65 nM respectively). Mediates recruitment of β-arrestin2 to GPR35. Also exhibits antinociceptive effects in a mouse model of visceral pain.

InChI:InChI=1/C23H16O6.2Na/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;;/h1-10,24-25H,11H2,(H,26,27)(H,28,29);;/q;2*+1/p-2

6640-22-8 Relevant articles

Stabilisation of pharmacologically active compounds in sustained release compositions

-

, (2008/06/13)

A pharmaceutical composition comprising ...

6640-22-8 Process route

Pamoic acid
130-85-8

Pamoic acid

embonic acid disodium salt
6640-22-8,7681-47-2,15537-67-4

embonic acid disodium salt

Conditions
Conditions Yield
With sodium hydroxide; In water;
 
impramine
50-49-7

impramine

Imipramine hydrochloride
113-52-0

Imipramine hydrochloride

embonic acid disodium salt
6640-22-8,7681-47-2,15537-67-4

embonic acid disodium salt

imipramine pamoate
10075-24-8

imipramine pamoate

Conditions
Conditions Yield
With sodium hydroxide; In water;
 

6640-22-8 Upstream products

  • 130-85-8
    130-85-8

    Pamoic acid

6640-22-8 Downstream products

  • 10075-24-8
    10075-24-8

    imipramine pamoate

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