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CasNo: 6640-22-8
MF: C23H14Na2O6
Appearance: pale yellow to yellow powder
Flammability and Explosibility |
Notclassified |
Biological Activity |
Pamoic acid disodium salt is a GPR35 agonist. Induces GPR35 internalization and activates ERK1/2 (EC50 values are 22 and 65 nM respectively). Mediates recruitment of β-arrestin2 to GPR35. Also exhibits antinociceptive effects in a mouse model of visceral pain. |
InChI:InChI=1/C23H16O6.2Na/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;;/h1-10,24-25H,11H2,(H,26,27)(H,28,29);;/q;2*+1/p-2
A pharmaceutical composition comprising ...
Pamoic acid
embonic acid disodium salt
Conditions | Yield |
---|---|
With sodium hydroxide; In water;
|
impramine
Imipramine hydrochloride
embonic acid disodium salt
imipramine pamoate
Conditions | Yield |
---|---|
With sodium hydroxide; In water;
|
Pamoic acid
imipramine pamoate